What is the Argus Safety Database?

The Argus safety database is a key part of the Argus Safety 3.0.1 pharmacovigilance software system. In a nutshell, pharmacovigilance is defined as the monitoring of any possible adverse effects of both herbal remedies and synthetic drugs as they are used.

The digital database is used to help companies ensure compliance with global regulations regarding pharmacovigilance and related activities. As a comprehensive pharmaceutical software system, it supports pharmacovigilance business processes that take place in both the pre- and post-marketing phases.

The Argus database is hosted in a data center that is ISO-9001-certified, and operates according to the security standards promulgated by FDA guidelines. By managing this data center, a pharmaceutical firm or laboratory may obtain maximum physical data security as well as access to effective data backup and recovery procedures whenever these services are needed.

ACCOVION, the full-service contract research organization that offers pharmacovigilance as a core service, has configured the Argus database with customized and validated rules to expedite safety reporting. This setup enables generated safety reports to be sent to regulatory investigators and central ethics committees.

The system covers a wide range of the most commonly used forms, including the American FDA MedWatch 3500A form for drugs, the VAERS form for vaccines, the CIOMS-I form, and many others utilized in European countries.

The standard setup in use by the Argus safety database system includes coding with current World Health Organization and MedDRA data dictionaries, as well as older versions of these dictionaries and many others to meet user requirements.

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The Leading Gaming PC Cases Are Essential To Help Protect and Power Your Extreme Gaming Hardware

Gaming PC Cases come in a variety of shapes and sizes. From rack mount to ATX tower casing, you can find one that best suits your gaming needs. Many games are played by as many 15-24 users and such games require the power of hardware to control both the graphics and many millions of instructions to the CPU with great speed. Custom Gaming PCs are the current rave with game lovers who strive for a better playing experience, adding more hardware.

With a large variety of casing, it is confusing to choose the right one. A good PC Case for gaming is one that has ample space to add more fans and USB ports. Heating is the main problem that slows down the PC and in some instances can damage it. Looks also matter a lot, an attractive and next-gen look, makes for a better playing experience.

All gaming PC cases come with microphones and headphone sockets, while the more advanced ones have fan controllers. New game players can do with two fans while some want to get additional fans to keep the PC from heating up. More advanced users utilize much of CPU power, and need more cooling.

When you are ready to buy a case, first look at the price options, compare various makes and models and see where you can save money and get the same functionality. The most accommodating case is considered the best. It will allow for more fans, and offers ample space for advanced graphic cards. Check to see, if the case can allow more than 4 fans and has at least two USB ports.

Some cases come with 4 USB ports and have space for up to six fans. If you are an advanced level player, you may want to consider one that has a fan speed controller, so you can monitor the cooling easily. Further up the ladder, there are cases that come with space for as many as 12 hard drives. Such a case, can take any kind of mother board you want to use.

The ATX are more popular these days and are like the industry standard. ATX form-factor allows for better air passage so all components can stay cool. It uses less cable, generates less heat and is more affordable. The expansion slots are easily accessible making it easy for users to add more graphic cards.

Looks wise, a clear panel looks attractive and spices up the computer using LEDs. There are also cases with bright graphics, and a modish look to add to the adventure. It all depends on your game choice, if you like a good thrill considering Gaming PC Cases that will add excitement to game time.

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What Requirements Does a Dot Net Developer Need to Fulfill?

Microsoft Dot Net is a useful software development component. It provides tools and libraries to the software developers so that they can create Windows-based applications in a more efficient manner. A Dot Net developer is a software programmer who has specific skills using .Net to develop software and computer applications. For people who are in the midst of looking for developers for your projects, there are some areas you need to take note. You are advised to look for competent programmers who can really assist you to complete your tasks successfully.

First thing first, you need to be clear about the responsibilities of a .Net Developer before you start looking for suitable candidate. Seriously speaking, the programmer is required to:

• Work hand in hand with other software engineers and architects to develop a logical series of instructions referred to as programming code for the computer to communicate with the networks, applications and databases.

• Create new software applications to suit the business needs

• Modify, repair, test and enhance existing applications

After knowing what the developer is required to do, the next area we need to take into consideration is the academic qualification. In general, a programmer should have degree qualification in computer science, information technology or any related discipline. If the programmer is not a degree holder, you may take a look at his or her working experience. If the candidate has extensive experience dealing with .Net development tools, you can consider getting him or her in. Check with the candidate whether he or she is familiar with maintenance of ASP Applications, e-Commerce solution, online education and learning, social networking sites, corporate web applications, and so on.

At the same time, a good dot net developer must be competent in carrying out all the important tasks. It is a must for him or her to have the following skills in:

• Classic ASP

• Microsoft SQL 2000 / 2005

• MS Access

• JavaScript, XML, DHTML, AJAX and CSS

• VBScript and JScript

Frankly speaking, if the programmer does not have the above mentioned skills, most of the employers in the job market are not willing to hire him or her.

Besides the skills, we should also take serious consideration on the general qualities of the programmers. They should have qualities as follow:

• Good passion in work

Having great interest in work is important. The programmers should love and enjoy what they are doing.

• Good learning attitude

Learning is a continuous process. We can’t stop at certain stage. Good developers must have positive attitude in learning. They must always grab the opportunities to learn new technology so that good applications can be adapted.

• Some “intelligence”

Honestly speaking, intelligence is something very subjective. What I mean here is the “personality” of the person. Being a programmer, he or she must be smart and sensitive to respond to all changes. It is important for a programmer to be open-minded and willing to take new challenges from time to time.

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How to Uninstall and Remove G DATA Antivirus Completely

G DATA Antivirus is a complete protection solution for your home computer. However, no matter the reason is that corrupt virus signatures may have caused it not to upgrade properly, it will not work regularly and needs to be repaired, or probably corrupt files are causing 100% CPU usage, etc. Like all other antivirus software, there also may be times when you have to uninstall and remove G DATA Antivirus.

The standard method of uninstalling G DATA Antivirus is from Windows built-in Add / Remove Programs, but sometimes the removal process will hang and you may be unable to remove this program from your computer, because some registry entries and spaces may still be left in Your system. In this case, if you wish to completely remove this antivirus, you have to delete all those sticky registry entries, processes, services, as well as related folders and files.

Removing all instances of this antivirus program can be extremely tricky and there is a risk of damaging the operating system if not done properly. Then you can try using a good removal tool to help you remove this program automatically in seconds. Perfect Uninstaller is one of such software. It works in a very simple manner. Aside from working to remove G DATA Antivirus, it can also get rid of other unwanted programs from your computer.

1. It offers a much quicker and easier way to completely remove programs which can not be removed through "Add / Remove Programs".
2. It completely deletes empty or corrupt registry entries.
3. It has the "force uninstall" function to forcibly uninstall corrupted or hidden programs.
4. It has the "Special Uninstall" function designed for some very specific programs in that list
5. It can restore the registry to a previous state, and restore files from the recycle bin (files deleted into the recycle bin).

Uninstall and remove G DATA Antivirus from your system before proceeding with the installation of the next antivirus that you would like to set up, otherwise the antivirus will conflict and give much trouble that you will not be able to recover Windows from the crash.

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How Car Mechanics Use Technology

Do you know why it’s important to find a good mechanic or a good repair shop to repair your car? The reason: it could save you hundreds of dollars in parts and labor! When we say a “good mechanic” or a “good repair shop”, we’re referring to mechanics who are equipped with the latest technology. You don’t want to entrust your car to a shop with outdated machinery and equipment because it will take longer to arrive at a diagnosis. And the longer a mechanic takes to make a diagnosis, the larger your bill for labor!

Remember that car mechanics charge by the hour.

Car repairs can cover any one or a combination of the following (note that this is not a complete repair list).

• Air conditioning checks

• Air bag checks

• Electrical wiring

• Cables

• Clutch service and repair

• Transmission repair

• Wheel Alignment

• Suspension

• Brakes

• Heating system

• Oil and lubrication

• Battery

• Power windows

Much of the troubleshooting that mechanics use to diagnose a problem is facilitated by car repair technology.

Ever noticed how some lights on your panel come on when something’s wrong? In most cases, an experienced mechanic will know immediately what the problem is, but there are instances where it will take sophisticated technology to lead to an accurate diagnosis.

Sophisticated technology comes in many forms and one popular one is troubleshooting software. Companies like Auto Tech have a software program that car owners can use to find out what is ailing their vehicle.

Most car owners who were cynical about software programs before should seriously consider purchasing a reliable car troubleshooting software program. For instance, some programs start out by asking you to input your car make and model number, the year of the car and what kinds of equipment it has. The software features a large database of information about all cars in the market and a car owner simply follows the steps when prompted. It employs what the industry calls a “tree diagnosis” where logical steps take you through the entire diagnosis process.

After you’ve keyed in your car’s profile, you use the drop down menu to choose the symptoms that your car is exhibiting. For instance, if you choose “squealing brakes”, the program mimics the squealing of brakes and if that’s the sound you hear, you confirm it and the program recommends a series of steps.

You may not really want to use a troubleshooting software, but imagine how much time and money you could save if you spoke to the mechanic intelligently, letting him know that you’re in the know.

Students who are studying towards certification buy certain tools of the trade. A couple of examples are Snap On and Mac Tools. These two are the most popular in the United States and Canada.

Mechanics now have a wide range of technology tools to help them understand car problems better: digital multimeters (electronic measuring), boroscopes (testing heat exchangers), fuel diagnostic testers (testing and balancing fuel injectors) and other such new technologies.

New car mechanic technologies help shorten the learning curve and speed up diagnosis so that the car owner isn’t saddled with too many labor hours.

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Mortgage Loan Origination Software – 10 Functions of Mortgage Banking

Regardless of a mortgage lending organizations’ size, mortgage loan software, data security solutions and automation tools and services should be able to assist with mortgage loan automation requirements. In today’s chaotic mortgage lending environment origination and document security systems need to be easily configured to emphasize a company’s special needs and increase efficiencies across all aspects of the loan origination process, allowing lenders to increase quality and productivity.

Technology-driven automation is the key to succeeding in the increasingly complex, deeply scrutinized mortgage industry. Web-based (Software-as-a-Service), Enterprise mortgage software that supports the ten primary functions in mortgage banking will provide lenders with the necessary competitive advantages to succeed in today’s mortgage industry.

Ten Primary Functions in Mortgage Banking

  1. Mortgage Web site design, implementation, and hosting to provide product, service, loan status, and company information to mortgage customers and business partners
  2. Online loan applications for gathering information from borrowers and business partners that issue loan terms, disclosures, and underwriting conditions
  3. Loan origination software for managing loan data, borrower data, property data, general status reporting, and calculations
  4. Interface systems to send and receive data from real estate service providers, such as credit reports, flood determinations, automated underwriting, fraud detection, and closing documents
  5. Internal automated underwriting system that is simple enough for originators and sophisticated enough for underwriting portfolio loan products
  6. Document generation for applications, upfront disclosures, business processes, and closing documents
  7. Integrated imaging that is used from loan origination to investor delivery and for file archiving
  8. Interest rate and fee generation along with program qualification guidelines
  9. Secondary marketing data tools to track loan revenue and investor relationships, including warehouse line management and interim servicing to complete the back-office system
  10. Reporting such as loan delivery, year-end fee reporting, and HMDA reporting for loan application disposition

Web-Based, enterprise mortgage software that supports the ten primary functions of mortgage banking simplifies compliance, maximizes operational efficiencies, and increases profitability.

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Best Windows 7 Optimizer That Can Stabilize and Improve Your Computer Performance

A system optimizer is a software designed to maintain the performance of your computer, fix software related problems and keep your computer stable and secure. The need of a system optimizer software in Microsoft Windows7 operating system is high. This is because Windows 7 itself is unable to maintain all the mentioned aspects without the help of third-party products.

We are going to learn what exactly Windows 7 optimizer software is.

The best Windows 7 optimizer software shall include all the following features:

1. Registry Cleaner to fix the registry related issues

2. System Cleaner to clean unnecessary stuff and free-up the disk space

3. Registry Defragmenter to defrag the system registry

4. Startup Manager to control the programs running when you turn on your computer

5. Backup & Restore feature to restore unfavourable registry changes

“Registry Cleaner” to Fix the Registry Related Issues

Windows Registry is a vital component in Microsoft Windows 7. It contains information stored by your operating system and installed software. For example, the default settings, changes you made to your computer, system information, runtime data, etc. are stored.

Registry Cleaner is a software that finds the junk entries in the registry, and repairs them as far as possible. Unfortunately, Windows 7 does not include a built-in registry cleaner. The registry cleaner software included in the best Windows 7 optimizer lets you scan the genuine registry problems and correct them. It thereby helps avoiding many runtime errors and problems, such as, File Not Found, etc.

“System Cleaner” to Clean Unnecessary Stuff and Free-Up the Disk Space

A System Cleaner software lets you find the files and stuff that have unnecessarily occupied the hard disk space.

The tasks, like installing a program, uninstalling, repairing or updating the existing programs, and even just running the installed programs many times create temporary files, log files that need not be kept after the corresponding operation is performed. Sadly, many programs do not itself delete such files and stuff and thus your hard disk space is used for such unproductive stuff. Using a system cleaner software included in best Windows 7 optimizer, you can easily and safely delete such temporary stuff.

“Registry Defragmenter” to Defrag the System Registry

You know the importance of the registry in Windows 7 operating system, as already discussed. The continuous access of a number of programs to the registry results in its fragmentation. It reduces the system performance and freezes your computer.

The best Windows 7 optimizer software includes a registry defragmenter that enables analyzing the registry fragmentation and afterwards defrags it. A reboot is required to perform this process and all other running programs and services must be terminated.

“Startup Manager” to Control the Programs when you Turn on your Computer

Running too many programs at the Windows startup, results in system freezing and slow performance. A Startup Manager, included in best Windows 7 optimizer, lets you monitor and control the programs that run each time your computer is started. It lets you disable or delete the unwanted program entries and enable only those who are necessary.

Backup & Restore Feature to Restore the Unfavourable Registry

While doing all the above steps, care must be taken that you have followed some precautionary measures first, so that any unfavourable registry change can be later restored and unwilling situations can be easily avoided. The best Windows 7 optimizer should include such a feature.

Best Windows 7 Optimizer Recommended by Worldwide Experts

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Mortgage Loan Origination Software – 10 Functions of Mortgage Banking

Regardless of a mortgage lending organizations’ size, mortgage loan software, data security solutions and automation tools and services should be able to assist with mortgage loan automation requirements. In today’s chaotic mortgage lending environment origination and document security systems need to be easily configured to emphasize a company’s special needs and increase efficiencies across all aspects of the loan origination process, allowing lenders to increase quality and productivity.

Technology-driven automation is the key to succeeding in the increasingly complex, deeply scrutinized mortgage industry. Web-based (Software-as-a-Service), Enterprise mortgage software that supports the ten primary functions in mortgage banking will provide lenders with the necessary competitive advantages to succeed in today’s mortgage industry.

Ten Primary Functions in Mortgage Banking

  1. Mortgage Web site design, implementation, and hosting to provide product, service, loan status, and company information to mortgage customers and business partners
  2. Online loan applications for gathering information from borrowers and business partners that issue loan terms, disclosures, and underwriting conditions
  3. Loan origination software for managing loan data, borrower data, property data, general status reporting, and calculations
  4. Interface systems to send and receive data from real estate service providers, such as credit reports, flood determinations, automated underwriting, fraud detection, and closing documents
  5. Internal automated underwriting system that is simple enough for originators and sophisticated enough for underwriting portfolio loan products
  6. Document generation for applications, upfront disclosures, business processes, and closing documents
  7. Integrated imaging that is used from loan origination to investor delivery and for file archiving
  8. Interest rate and fee generation along with program qualification guidelines
  9. Secondary marketing data tools to track loan revenue and investor relationships, including warehouse line management and interim servicing to complete the back-office system
  10. Reporting such as loan delivery, year-end fee reporting, and HMDA reporting for loan application disposition

Web-Based, enterprise mortgage software that supports the ten primary functions of mortgage banking simplifies compliance, maximizes operational efficiencies, and increases profitability.

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Examples Of Spyware And What They Are

Spyware is a general term used to describe software that performs certain behaviors such as advertising, collecting personal information, or changing the configuration of your computer, generally without appropriately obtaining your consent first.

Spyware is often associated with software that displays advertisements (called adware) or software that tracks personal or sensitive information.

That does not mean all software that provides ads or tracks your online activities is bad. For example, you might sign up for a free music service, but you “pay” for the service by agreeing to receive targeted ads. If you understand the terms and agree to them, you may have decided that it is a fair tradeoff. You might also agree to let the company track your online activities to determine which ads to show you.

Other kinds of Spyware make changes to your computer that can be annoying and can cause your computer slow down or crash.

These programs can change your Web browsers home page or search page, or add additional components to your browser you don’t need or want. These programs also make it very difficult for you to change your settings back to the way you originally had them.

The key in all cases is whether or not you (or someone who uses your computer) understand what the software will do and have agreed to install the software on your computer.

There are a number of ways Spyware or other unwanted software can get on your computer. A common trick is to covertly install the software during the installation of other software you want such as a music or video file sharing program.

Any software that covertly gathers user information through the user’s Internet connection without his or her knowledge, usually for advertising purposes. Spyware applications are typically bundled as a hidden component of freeware or shareware programs that can be downloaded from the Internet; however, it should be noted that the majority of shareware and freeware applications do not come with SpyWare. Once installed, the Spyware monitors user activity on the Internet and transmits that information in the background to someone else. Spyware can also gather information about e-mail addresses and even passwords and credit card numbers

Aside from the questions of ethics and privacy, SpyWare steals from the user by using the computer’s memory resources and also by eating bandwidth as it sends information back to the spy ware’s home base via the user’s Internet connection. Because SpyWare is using memory and system resources, the applications running in the background can lead to system crashes or general system instability.

Because SpyWare exists as independent executable programs, they have the ability to monitor keystrokes, scan files on the hard drive, snoop other applications, such as chat programs or word processors, install other SpyWare programs, read cookies, change the default home page on the Web browser, consistently relaying this information back to the SpyWare author who will either use it for advertising/marketing purposes or sell the information to another party.

Licensing agreements that accompany software downloads sometimes warn the user that a SpyWare program will be installed along with the requested software, but the licensing agreements may not always be read completely because the notice of a SpyWare installation is often couched in obtuse, hard-to-read legal disclaimers.

Examples of SpyWare

These common SpyWare programs illustrate the diversity of behaviors found in these attacks. Note that as with computer viruses, researchers give names to SpyWare programs which may not be used by their creators. Programs may be grouped into “families” based not on shared program code, but on common behaviors, or by “following the money” of apparent financial or business connections. For instance, a number of the SpyWare programs distributed by Claria are collectively known as “Gator”. Likewise, programs which are frequently installed together may be described as parts of the same SpyWare package, even if they function separately.

o CoolWebSearch, a group of programs, takes advantage of Internet Explorer vulnerabilities. The package directs traffic to advertisements on Web sites including coolwebsearch.com. It displays pop-up ads, rewrites search engine results, and alters the infected computer’s hosts file to direct DNS lookups to these sites.

o Internet Optimizer, also known as DyFuCa, redirects Internet Explorer error pages to advertising. When users follow a broken link or enter an erroneous URL, they see a page of advertisements. However, because password-protected Web sites (HTTP Basic authentication) use the same mechanism as HTTP errors, Internet Optimizer makes it impossible for the user to access password-protected sites.

o Zango (formerly 180 Solutions) transmits detailed information to advertisers about the Web sites which users visit. It also alters HTTP requests for affiliate advertisements linked from a Web site, so that the advertisements make unearned profit for the 180 Solutions Company. It opens pop-up ads that cover over the Web sites of competing companies.

o HuntBar, aka WinTools or Adware,WebSearch was installed by an ActiveX drive-by download at affiliate Web sites, or by advertisements displayed by other SpyWare programs-an example of how SpyWare can install more SpyWare. These programs add toolbars to IE, track aggregate browsing behavior, redirect affiliate references, and display advertisements.

oZlob Trojan or just Zlob, Downloads itself to your computer via ActiveX codec and reports information back to Control Server. Some information can be as your search history, the Websites you visited, and even Key Strokes.

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Can You Upgrade a Maya Student Version to a Full Commercial Edition?

The Maya 3D software from Autodesk has long-been a staple tool for the production of the highest level of Visual Effects and animation for Oscar-winning blockbuster movies, TV shows and video games.

Students who are looking to secure themselves commercial work upon graduation these days typically need to show some familiarity with this software…ideally the more the better, since most companies these days use Maya as their main software package, and many have it deeply integrated into their own proprietary pipelines and tools – meaning that the situation is unlikely to change for the foreseeable future.

Students who take the opportunity currently afforded them of purchasing a copy of the Maya Student Edition do well since they are able to improve their skillset on the full Unlimited version of the software, and do so at a huge discount (the student edition typically retails for around $350).

However, a number of students wonder if they also qualify for a discount later on if they wish to upgrade to a full commercial edition of the Maya software. Jumping from graduation to commercial work can be a challenge, so any way to alleviate the expense of setting yourself up as a freelancer is more than welcome…but can it actually be done?

Upgrade Maya Student Edition To Commercial License?

Yes, you’ll be pleased to know that there is a program available where current owners of a Maya student license are able to upgrade to the full commercial license at a massive discount of around 60%…in other words, a full commercial license of Maya would typically cost around $3,900, but student license holders are able to upgrade their current license to a full commercial one for just $1,300.

This is huge, and can be a real lifesaver for folks who want to go it alone and start their own freelance business but are wary of the huge costs involved.

In fact, if you’re smart about it and don’t mind a little negotiation, the license could even be purchased with a down-payment from your first client before you even begin working on their project.

Such a huge discount on the student to commercial upgrade is a great incentive for students, especially at this economic time, and it also makes purchasing the Maya student edition in the first place a sensible option, since you get access to these kinds of discounted upgrades.

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